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Quantifying the Benefits of Digital Biomarkers and Technology-Based Study Endpoints in Clinical Trials: Project Moneyball


August 03, 2022

Discussion Topic

Have you ever been asked what tangible benefits digital biomarkers bring to clinical studies? Inspired by the book and film Moneyball, the authors developed a novel method to quantify the values of patient selection and endpoint technologies using Monte Carlo simulation. Their work illustrates the model and potential application using Parkinson’s Disease example. This presentation will discuss:
1. The project rationale and Moneyball metaphor
2. SV95C and its clinical study impact
3. Monte Carlo approach and the model
4. The results and the way forward

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